HIGHLIGHTED TOPIC Regulation of Protein Metabolism in Exercise and Recovery Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men
نویسندگان
چکیده
Juha J. Hulmi, Jörgen Tannerstedt, Harri Selänne, Heikki Kainulainen, Vuokko Kovanen, and Antti A. Mero Department of Biology of Physical Activity and Neuromuscular Research Center, University of Jyväskylä, Jyväskylä, Finland; Åstrand Laboratory, Swedish School of Sport and Health Sciences and Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden; LIKES Research Center, Jyväskylä, Finland; and Department of Health Sciences, University of Jyväskylä, Jyväskylä, Finland
منابع مشابه
Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men.
Signaling pathways sense local and systemic signals and regulate muscle hypertrophy. The effects of whey protein ingestion on acute and long-term signaling responses of resistance exercise are not well known. Previously untrained young men were randomized into protein (n = 9), placebo (n = 9), and control (n = 11) groups. Vastus lateralis (VL) muscle biopsies were taken before and 1 h and 48 h ...
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Tang JE, Moore DR, Kujbida GW, Tarnopolsky MA, Phillips SM. Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men. J Appl Physiol 107: 987–992, 2009. First published July 9, 2009; doi:10.1152/japplphysiol.00076.2009.— This study was designed to compare the acute response of mixed muscle pro...
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Objective: Intense muscle contractions are associated with oxidative stress and immune system deficiency, especially in the presence of obesity. This study aimed to determine the effect of whey protein supplementation following eccentric resistance contractions on some determinants of oxidative stress in non-athletic obese students. Materials and Methods: In this double blinded randomized clin...
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Leucine ingestion reportedly activates the mTOR pathway in skeletal muscle, contributing to a hypertrophy response. The purpose of the study was to compare the post-resistance exercise effects of leucine and whey protein supplementation on endocrine responses and muscle mTOR pathway phosphorylation. On visit 1, subjects (X±SD; n=20; age=27.8±2.8yrs) provided baseline blood samples for analysis ...
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The effect of resistance exercise with the ingestion of supplementary protein on the activation of the mTOR cascade, in human skeletal muscle has not been fully elucidated. In this study, the impact of a single bout of resistance exercise, immediately followed by a single dose of whey protein isolate (WPI) or placebo supplement, on the activation of mTOR signalling was analyzed. Young untrained...
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